This remarkable result is not well known outside a small circle of sleep researchers for three good reasons. First, sleep deprivation is not as convenient as taking a pill. Second, prolonged sleep deprivation is not exactly a desirable state; it leads to cognitive defects, such as reduced working memory and impaired decision making. Finally, depression recurs after the mother, inevitably, succumbs to sleep, even for a short nap. Nonetheless this is an incredibly important observation; it shows that depression can be rapidly reversed and suggests that something is happening in the sleeping brain to bring on episodes of depression.”

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[Fascinating as a short-term means to dampening pain – but one still has to wait till nighttime to lose any sleep. -Ed.]

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[A wonderful follow-up to this post. Props to Cathy Horyn, who really hits all the bases in writing responsibly about a suicide.]

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Read Judi’s Blog, Life As A Hospice Patient

Americans live in a political, social, and historical context that advances personal freedom, choice, and self-determination above all else,” write authors Hazel Rose Markus (Stanford University) and Barry Schwartz (Swarthmore College). “Contemporary psychology has proliferated this emphasis on choice and self-determination as the key to healthy psychological functioning…”

“Moreover, the enormous opportunity for growth and self-advancement that flows from unlimited freedom of choice may diminish rather than enhance subjective well-being… Even in contexts where choice can foster freedom, empowerment, and independence, it is not an unalloyed good. Choice can also produce a numbing uncertainty, depression, and selfishness.”

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[Ironically, we solve this dilemma by choosing to limit our choices. Shopping for clothes used to be a nightmare for me, because I didn't know where to begin – until I learned to take my whims more seriously. Once I started dismissing most things out of hand (often with no good reason), I could get choosing underway. -Ed.]

Popular Drugs May Help Only Severe Depression

A headline from two years ago in Nature:

SSRIs show efficacy over placebo only in the most severely depressed patients

Drug companies exaggerate and even fictionalize their drugs’ benefits. This is not news.

I’m not against the use of these drugs, but their reckless promotion leaves a sour taste. Who are these drugs made for, exactly? When I take one of these pills, who stands to gain? These are always good questions to ask. Pills can work, and in the severest cases they’re necessary despite risks. But in the battle for peace of mind, no drug is an easy answer. Adam Phillips says it best: “Havoc is always wreaked in fast cures for confusion.”

[Update: As usual, Jonah Lehrer has a clever take from a year ago. -Ed.]

Those patients with schizophrenia who are more intelligent and better educated, for example, who perform better on measures of abstract reasoning, and who demonstrate greater insight into the nature of their illness, are more likely to kill themselves [my emphasis]. Patients who do well socially and academically when young and who then are hit by devastating illnesses such as schizophrenia or manic-depression seem particularly vulnerable.

In other words: smart, sociable, over-achivers can be just as suicidal as withdrawn folks once illness hits – and often times illness isn’t given much expression. Jamison goes on to stress that many people fool their peers expertly, despite the darkest of feelings. Here she is again, in the book’s prologue, writing of her own ordeal:

Because the privacy of my nightmare had been of my own designing, no one close to me had any real idea of the psychological company I had been keeping. The gap between private experience and its public expression was absolute; my persuasiveness to others was unimaginably terrifying.

The point is, we are terrible at judging “the kind of person who would do such a thing” – especially parents when it comes to their own children (understandably so). We need to shed the mindset that we can grasp suicide, that we can see it coming. We need to open ourselves up to surprise. Suicide is not the province of the preternaturally depressed. It is, in a sense, all around us.

‘The idea that a drug designed to alleviate physical pain should reduce the pain of social rejection seemed simple and straightforward based on what we know about neural overlap between social and physical pain systems. To my surprise, I couldn’t find anyone who had ever tested this idea,’ DeWall said.

According to a study due to be published in the journal Psychological Science, DeWall and colleagues were correct. Physical and social pain appear to overlap in the brain, relying on some of the same behavioral and neural mechanisms…

Hurt feelings and social pain decreased over time in those taking acetaminophen, while no change was observed in subjects taking the placebo. Levels of positive emotions remained stable, with no significant changes observed in either group. These results indicate that acetaminophen use may decrease self-reported social pain over time, by impacting emotions linked to hurt feelings.

‘We were very excited about these initial findings,’ DeWall said.”

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[Because emotional pain feels less localized and more abstract, we're inclined to disregard it as something different from "real" pain. We take it less seriously as an injury – i.e., as a treatable medical condition. These findings are a nice counterpoint to that impulse. -Ed.]

And sometimes when I’m feeling kind of overwhelmed by ‘the battlefield,’ I will just sort of stay away from the artificial situations and get back to my closer friends who really get what’s going on in my psyche.”

[Amen. I'm going to make better sleep hygiene my new year's resolution. -Ed.]

I pride myself in keeping an open mind about mental illness, but I have to admit that it’s tough to watch this video without feeling a pang of conservative rage. Where are we going with all of this? Are we so desperate and starry-eyed that we’re willing to experiment on our own children?? Don’t they deserve a more cautious approach?!??!?!

I’m not quick to judge any of the parents. My heart goes out to them. I’ve never had a kid, let alone one with mental illness. But I do know something of the helplessness that surrounds families in the midst of these crises. It’s a God-awful experience – and a dangerous one, too. Feelings of abject helplessness lead to extreme vulnerability. And that’s exactly what you see in this video: vulnerable families being pressured into troubling treatment, all at the behest of powerful institutions with their own interests to weigh. I’m not skeptical of doctors or “experts” (that’s a strain of American fundamentalism I could live without), but at the same time we have to recognize our respective roles. A child’s care is the sole responsibility of his or her parents. The educational system and the health care industry, despite what they advertise, were not designed to care for any particular child. Those institutions have competing priorities (the profit initiative, organizational flow, etc.), including millions of other kids. What is good for a school or a doctor’s office might be at odds with what is good for a child. When it comes to medicating our youth, we should be especially vigilant about these conflicts of interest, and wise to how good people’s judgment can go bad.

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[Note the segment tiles above the video display; to watch the whole program, click on each segment.]